DC1 — Cellular mechanisms of inflammation resolution in rheumatoid arthritis

This project aims to unravel how synovial macrophages and fibroblasts coordinate the resolution of inflammation in rheumatoid arthritis. The doctoral candidate will investigate the cellular and molecular pathways that fail during chronic inflammation using patient-derived samples, advanced single-cell and spatial transcriptomic technologies, and experimental models. The project combines immunology, systems biology and translational rheumatology to identify novel pro-resolving mechanisms and therapeutic targets. The candidate will work within the international HARPNET consortium and collaborate closely with leading academic and industrial partners in inflammation research.