DC12 — Small-molecule promoters of inflammation resolution

DC12 — Small-molecule promoters of inflammation resolution
DC12
Status: Open
Supervisor
Professor Trond V. Hansen
Host Institution
University of Oslo
City
Oslo
Country
Norway

About this Project

This medicinal-chemistry project will design, synthesise and characterise small molecules that activate pro-resolving pathways, focusing on GPR101 and its endogenous ligand RvD5n-3 DPA. Candidates will be optimised for biological activity, stability and drug-like pharmacological properties.

Your profile and what you'll gain

Skills required

Background in organic chemistry, medicinal chemistry, pharmaceutical chemistry or chemical biology; practical synthetic chemistry experience and interest in computational drug design.

Skills acquired

Computer-aided molecular design, docking and molecular dynamics, multistep organic synthesis, compound purification and characterisation, structure-activity relationships, receptor pharmacology, preclinical efficacy testing, pharmacokinetics and metabolic-stability analysis.

Eligibility Criteria

Before applying, candidates should ensure they meet the following eligibility criteria:

  • have a MSc degree in Life Sciences or obtain a MSc degree by October 2026
  • have completed a research internship with relevant expertise
  • have obtained high grades during his/her studies
  • be fluent in English (some countries may also require language certifications – this will be communicated to applicants following shortlisting)
  • applicant must not have resided in the country of the recruiting organisation for more than 12 months preceding the recruitment date
Supervisor
Professor Trond V. Hansen
Open
Host Institution
University of Oslo
City
Oslo
Country
Norway

Ready to apply?

One application, up to three project choices.

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